CONCLUSIONS: Clinicians identified critical informational, contextual, and design requirements for a clinical decision support tool to promote timely palliative care in heart failure. These findings directly inform tool design, workflow integration, and implementation strategies, and will guide future pilot testing and clinical evaluation.
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Associations of psychosocial factors with cardiovascular health in aging: insights from the Inlife-Aging Project
Life’s Essential 8 (LE8) provides a multidimensional framework to assess cardiovascular health (CVH) in aging populations. The objective of this study was to describe LE8 component scores and their variation by age, sex, and psychosocial factors in middle-aged and older adults from Cádiz, Spain. Cross-sectional data were analyzed from 495 adults aged 50-79 years (59.4% women; 34.7% ≥ 65 years). LE8 scores were calculated following American Heart Association guidelines. Group comparisons used…
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Cancer and heart failure: prevalence, incidence, and prognosis in Scotland
CONCLUSIONS: Patients with HFexp have a slightly higher risk of cancer overall, but this may vary according to cancer type. Patients with both cancer and HFexp have a poor prognosis with a similar proportion of deaths attributed to cancer and cardiovascular disease.
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Dose- and size-dependent effects of microplastics in a simplified mast-cell model of inflammation
Micro- and nanoplastics have been recognized to pose potential threat for human environment and health. Plastic particles of different, sizes, forms and composition have already been detected in human tissue, but little information is available so far on how particle numbers are relating to cellular effects in dependence of size. We here set out to utilize a mast-cell/basophilic cell model to investigate the role of different polystyrene bead numbers and sizes on mast-cells under conditions that…
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