Research - RCS Experience

Sex-specific clinical profiles in patients with acute ischemic stroke and chronic kidney disease

CONCLUSION: Patients with AIS demonstrated distinct sex-associated clinical profiles according to CKD status. Although several associations were numerically stronger among patients with CKD, formal interaction testing did not establish statistically significant effect modification. These findings characterize clinical heterogeneity among men and women with established AIS and warrant further investigation to determine whether these profiles have implications for treatment or outcomes.

Deaths involving chronic obstructive pulmonary disease and cardiac arrest in older US adults, 1999-2023: A retrospective cross-sectional study

National long-term trends and disparities in deaths in which both chronic obstructive pulmonary disease (COPD) and cardiac arrest are recorded on death certificates are not well characterized. We used CDC WONDER Multiple Cause of Death data (1999-2023) to identify US adults aged ≥ 65 years whose death certificates listed both COPD (ICD-10 J41-J44) and cardiac arrest (I46) as underlying or contributing causes. Age-adjusted mortality rates (AAMRs) were stratified by sex, race/ethnicity, region,…

Dietary Components as Promising Candidates for Mitigating Micro- and Nanoplastic-Associated Metabolic Dysfunctions

Global plastic production has potentially led to pervasive micro- and nanoplastic (MNP) exposure across environmental, agricultural, and biological systems, now detected in every human tissue examined, from blood and placenta to brain and cardiovascular plaque, raising potential public health concerns. Given their small size and physicochemical properties, MNPs can infiltrate soil and water, enter plants and animals, and transfer along food and water systems, potentially reaching human tissues….

Plastics in Human Reproductive Tissues: A Systematic Review of Detection, Characterization, and Effects on Fertility

CONCLUSION: The findings of this review show that MPs and NPs accumulate in human reproductive tissues and may induce cellular dysfunction. Additional investigations into the impact of MPs and NPs on ovarian reserve markers and reproductive outcomes are needed to better understand the potential impacts of plastic particle exposure on reproductive health.