Research - RCS Experience

Inhalation toxicity of nanoplastics: mechanistic insights from biophysical barrier disruption to chronic lung diseases

Airborne nanoplastics (NPs) are increasingly recognized as an emerging respiratory health concern because their small size enables deposition in the distal lung, where they can interact directly with the alveolar microenvironment. However, the sequence of mechanisms linking their initial physicochemical interactions to chronic pulmonary outcomes remains insufficiently defined. This review integrates recent evidence to propose a mechanistic framework connecting early biophysical barrier…

Spontaneous Multivessel Coronary Artery Dissection in a Middle-Aged Nigerian Male Patient With Chest Pain: A Case Report From Nigeria

Spontaneous coronary artery dissection (SCAD) is now more frequently recognized as an etiology of acute coronary syndrome, primarily reported in women. Its occurrence in men remains rare and often goes unnoticed and underreported, especially in low- and middle-income countries like Nigeria, where limited access to advanced coronary imaging and low clinical suspicion hinder diagnosis. A 46-year-old Nigerian man was admitted with acute chest discomfort, T-wave abnormalities on electrocardiography…

Physical profiling in elite professional men’s football: Academy, reserve and first team variations in fitness and performance

We profiled the physical fitness and training and match performance of elite academy (under-18 (U18, n = 23), reserve (RES, n = 15)), and first teams (FT, n = 25) to assess physical readiness for academy-FT progression. Further, we segregated players into player positions, ages, and current versus former academy players that had successfully progressed to FT. Aerobic capacity, anthropometry, and global positioning system- and heart rate-derived performance profiles in training and matches…

Sex Differences in a Contemporary, Real-World Cohort of Patients with Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis

CONCLUSIONS: In this analysis of contemporary patients with ATTR-CM treated with tafamidis, women represented a small proportion of the overall population, and a greater proportion had ATTRv-CM compared with men. Although women appeared more symptomatic at presentation, men had a higher risk of all-cause mortality.