Micro/nanoplastics pollution: emerging challenges for aquatic animals and food crops

Micro/nanoplastics pollution: emerging challenges for aquatic animals and food crops

Recent reports from worldwide reveal that micro/nanoplastics (MNPs) are pervasive pollutants affecting all ecosystems and a wide range of organisms, including animals, plants, fish, humans, and microorganisms. MNPs have been detected in food items, mother milk, vegetables, and other consumable products, indicating their potential to impact organisms across all life stages. These particles can enter the body through inhalation, ingestion, and dermal contact. Due to their small size,…
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Human Exposures to Micro- and Nanoplastics in Water and Data Needed to Understand Potential Health Effects-A-State of the Science Review

Human Exposures to Micro- and Nanoplastics in Water and Data Needed to Understand Potential Health Effects-A-State of the Science Review

Human exposure to micro- and nanoplastics (MNPs) in the environment and their potential health effects are of growing public interest. Regarding water, that interest grows because multiple studies found MNPs in different matrices including tap and bottled water. We intended to (i) understand how MNPs enter freshwater systems and drinkable water, (ii) assess the evidence of human exposure to MNPs in water, and (iii) identify data gaps to support the determination of potential health effects. We…
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Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation

Nanoplastics and Neurodegeneration: A Roadmap From Mechanism to Causation

Nanoplastics are ubiquitous by-products of global plastic production and have emerged as a potentially consequential yet insufficiently defined threat to health. Recent studies have revealed that these synthetic particulates can cross the blood-brain barrier, accelerate amyloid aggregation, impair microglial clearance, hijack the gut-liver-brain axis, and drive neuroinflammation-mechanisms central to neurodegeneration in Alzheimer’s and Parkinson’s disease. In addition, anionic nanoplastics can…
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Toxicological effects of polypropylene nanoparticles similar in size to nanoplastics in plastic-bottled injections on mice and zebrafish

Toxicological effects of polypropylene nanoparticles similar in size to nanoplastics in plastic-bottled injections on mice and zebrafish

Nanoplastics may threaten human health, most current toxicological studies focus on polystyrene, but no study on polypropylene (PP) in plastic bottled injections for medical care. Based on the amount of nanoplastic from PP-bottled injections introduced by intravenous infusion average daily in infants (31.5 ng) and adolescents (157.5 ng), we explored the toxicological effects of PP-NPs on the organ development of zebrafish. We also investigated the toxicological effects in mice of PP-NPs at doses…
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