Tag Archives: MicroPlastics

Polyvinyl chloride nanoplastics (PVC-NPs) are emerging pollutants that pose a significant threat to agricultural soils, where they may disrupt rhizosphere volatile organic compound (VOC) signaling and intensify rice blast disease caused by Magnaporthe oryzae. The widespread use of PVC-NPs may result in their accumulation in rice-cultivated soils, where their physicochemical properties interfere with and adversely affect the soil microbial communities and root physiology. Evidence from recent…

Nanoplastics pose emerging health risk, yet no existing analytical method can quantitatively detect sub‑300 nm nanoplastics in human urine, mainly due to insufficient sensitivity and polymer-dependent limitations. Here, we report a catalase (CAT)‑based electrochemical sensing platform that enables the first quantitative detection of sub‑300 nm nanoplastics in human urine. The sensor leverages a nanoplastic‑induced structural perturbation mechanism, in which hydrophobic‑dominant and…

Widespread environmental contamination with nanoplastics (NPs) poses a significant risk to human health, particularly their accumulation in the central nervous system (CNS). This review examines how NPs can breach biological barriers, including the blood-brain barrier (BBB), olfactory system, and gut-brain axis, to access the brain. After their uptake by neurons through endocytosis, NPs primarily accumulate in the mitochondria, triggering cascades of neurotoxic changes in the brain. Existing…

Among environmental pollutants, microplastics (MPs) and nanoplastics (NPs) represent a major threat to marine and terrestrial ecosystems because of their widespread distribution, environmental persistence, accumulation in animal and human organs, and toxicity. MPs and NPs target the major endocrine components, including the hypothalamic-pituitary-adrenal (HPA) and gonadal (HPG) axes, thus affecting steroid milieu with repercussions for peripheral endocrine glands and brain functions. Steroid…

CONCLUSIONS: Our findings demonstrated that PS-NPs exposure aggravated retinal inflammation and photoreceptor degeneration by microglial SPP1 signaling activation and NETs formation, underscoring new insights into the effects and potential targets of MNPs exposure on retinal disorders.

Micro- and nanoplastics (MNPs) are widespread environmental pollutants, with increasing evidence of human exposure through multiple routes. Their detection in human tissues, including the lungs, raises concerns about their potential impact on respiratory health, including lung cancer (LC). This review synthesizes current evidence on the biological effects of MNP exposure, with a focus on mechanisms potentially relevant to LC. In particular, extracellular vesicles (EVs) are discussed as mediators…

Chronic inhalation exposure to nanoplastics, specifically polyethylene terephthalate (PET) nanoplastics (PET-NPLs) is an emerging health concern, yet the long-term consequences for genomic stability and DNA damage response (DDR) capacity in bronchial epithelial cells remain poorly characterized. For this study, human bronchial epithelial BEAS-2B cells were continuously exposed to PET-NPLs for over 20 weeks, after which elevated basal DNA genotoxic damage was observed, as assessed by the alkaline…

Concerns about human exposure to micro- and nanoplastics (MNPLs), particularly nanoplastics (NPLs), have intensified in recent years. Consequently, there is a growing need for validated quantitative analytical methods capable of assessing NPLs in complex human biological matrices. Current approaches for NPL analysis are still limited by the absence of standardised protocols, difficulties in avoiding background contamination, and challenges associated with the selective identification and…

The pervasive environmental presence of micro- and nanoplastics (MNPs), combined with their ability to cross biological barriers and accumulate in the brain, has raised significant concerns regarding their neurotoxic potential. While neuroinflammatory and neurodegenerative effects are increasingly documented, a focused synthesis of their impact on depression-relevant behaviors is lacking. This systematic review evaluates the evidence linking MNPs exposure to depressive-like phenotypes across…

The widespread occurrence of microplastics (MPs) and nanoplastics (NPs) in natural environments, along with their associated potential health risks, has garnered significant scientific interest. Compared to MPs, NPs have a smaller particle diameter and a substantially larger surface-to-volume ratio. Therefore, NPs are hypothesized to pose a greater risk than MPs. In this study, we employed a multimodality approach combining pre-processing, transmission electron microscopy, and energy-dispersive…