Category Archives: Men’s Health

CONCLUSIONS: The large increase in all-cause mortality during the pandemic was driven by deaths coded as COVID-19. The lack of excess mortality from the major groups of chronic diseases suggests that the health system coped well with these conditions. The marked rise in deaths from conditions which have been linked with mitochondrial dysfunction merits further investigation.

CONCLUSIONS: Sex did not modify the comparative effectiveness of DCB versus thin-strut DES for ISR, on the composite endpoint or on any component; these data do not support sex-based device selection. Wide intervals and differential follow-up establish the absence of detectable heterogeneity rather than equivalence.

BACKGROUND: Extracellular matrix (ECM) dysregulation, manifesting as fibrosis or tissue destruction, is a hallmark of many chronic diseases, leading to organ dysfunction and mortality. However, ECM-related diseases are rarely considered as a unified group, and their burden remains poorly defined. We aimed to quantify the burden of ECM-related diseases by estimating prevalence and mortality.

IntroductionWe conducted a pilot study of older cannabis users with problematic or frequent (i.e. ≥4/7 days/week) use as a preliminary test of the hypothesis that compared to men, women would demonstrate greater stress reactivity and dementia risk.Methods47 participants ages 50-75 (55.3% male, 68% with cannabis use disorder) completed the Trier Social Stress Test, neuropsychological testing, 3T brain MRI, and blood draw.ResultsMen demonstrated: greater salivary cortisol, systolic blood pressure,…

CONCLUSION: PhA was independently associated with aerobic work capacity after accounting for body composition, muscle mass, muscle function, and disease-related variables. The association with absolute aerobic work capacity differed by sex, whereas no clear effect modification by age range was observed.

Despite growing recognition of sex disparities in cardiovascular disease (CVD), contemporary, harmonized analyses of sex-specific burden in the European region that could inform targeted prevention strategies, remain limited. Sex-specific patterns in CVD burden and risk factor exposure across 55 European Society of Cardiology (ESC) member countries were examined using data from the 2023 Global Burden of Disease study. Risk factor exposure was quantified using age-sex-standardized summary…

CONCLUSIONS: This Phe-WAS demonstrates the broad spectrum of health care interactions in AF beyond traditional cardiovascular complications.

CONCLUSION: The CDPBA provides a novel, interpretable approach to biological age estimation based on cardiovascular disease hospitalization risk.

CONCLUSIONS: Up to half of real-world patients with newly diagnosed mHSPC would have been ineligible for RCT participation, yet many received therapies despite trial ineligibility. This highlights the need for more inclusive and representative research and a comprehensive examination of real-world data for clinical decision-making.

CONCLUSION: A single screening ECG identified previously unrecognized AF, including individuals who would meet a guideline-based threshold for consideration of anticoagulation after clinical evaluation. These findings describe the potential yield of opportunistic AF detection in this primary-care setting but do not establish population-level screening effectiveness or clinical benefit.